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Hyperaldosteronism, also aldosteronism, is a medical condition where too much aldosterone is produced by the adrenal glands, which can lead to lowered levels of potassium in the blood.
In endocrinology, the terms primary and secondary are used to describe the abnormality (e.g. elevated aldosterone) in relation to the defect, i.e. the tumor’s location. The adjective primary refers to an abnormality that directly leads to pathology, i.e. aldosteronism is caused by the apparatus that generates aldosterone. Secondary refers to an abnormality that indirectly results in pathology through a predictable physiologic pathway, i.e. a renin producing tumor leads to increased aldosterone, as the body’s aldosterone production is normally regulated by renin levels.
One form has been linked to 7p22.[1]
It can be asymptomatic, but the following symptoms can be present
Treatment includes Spironolactone, a K+ sparing diuretic that works by acting as an aldosterone antagonist.
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