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A glioma is a type of cancer that starts in the brain or spine. It is called a glioma because it arises from glial cells. The most common site of gliomas is the brain.[1]
Gliomas are classified by cell type, by grade, and by location.
Gliomas are named according to the specific type of cell they most closely resemble. The main types of gliomas are:
Gliomas are further categorized according to their grade, which is determined by pathologic evaluation of the tumor.
Of numerous grading systems in use, the most common is the World Health Organization (WHO) grading system for astrocytoma. The WHO system assigns a grade from 1 to 4, with 1 being the least aggressive and 4 being the most aggressive. Various types of astrocytomas are given corresponding WHO grades.
The prognosis is the worst for grade 4 gliomas, with an average survival time of 12 months. Overall, few patients survive beyond 3 years.[2] [3]
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