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The dysfibrinogenemias are a group of autosomal dominant disorders of qualitatively abnormal fibrinogens. There are various different fibrinogen abnormalities, each named after the place where it was discovered. Each dysfibrinogenemia is associated with slightly different effects on the thrombin time and on normal clotting. Some dysfibrinogenemias cause abnormal bleeding or even thrombosis, while others have no effect on either bleeding or thrombosis. Some examples are:
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