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Dermatofibromas (also known as a “Fibrous histiocytoma”[1]:611 ) are harmless benign skin growths, found especially on the legs, that range in size from about 0.5 to 2 cm.
They are hard papules (rounded bumps) that may appear in a variety of colors, usually brownish to tan. Although typical dermatofibromas cause little or no discomfort, itching and tenderness can occur. Some physicians and researchers believe dermatofibromas form as a reaction to previous injuries such as insect bites or thorn pricks.[citation needed] They are composed of disordered collagen laid down by fibroblasts. In rare cases, basal cell carcinoma may develop in a dermatofibroma.
Deep penetrating dermatofibroma may be difficult to distinguish, even histologically, from rare malignant fibrohistocytic tumours like dermatofibrosarcoma protuberans.[2]
Dermatofibromas occur most often in women; the male to female ratio is about 1:4.[citation needed]
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