Read more about this disease, some with Classification – Types – Signs and symptoms – Genetics – Pathophysiology – Diagnosis – Screening – Prevention – Treatment and management – Cures and much more, some including pictures and video when available.
Fraser syndrome, also called Meyer-Schwickerath’s syndrome, Fraser-François syndrome,[1] or Ullrich-Feichtiger syndrome, is an autosomal recessive[2] congenital disorder.
It is characterized by developmental defects including underdevelopment of the eyes (cryptophthalmos) and the genitals (micropenis, cryptorchidism or clitoromegaly).[3]
Congenital malformations of the nose, ears,larynx, and renal system as well as mental retardation are manifest occasionally.
The genetic background of this disease has been linked to a gene called FRAS1, which seems to be involved in skin epithelial morphogenesis during early development.[4]
It has also been associated with FREM2.[5]
It is named for George Fraser.[6]
[tubepress mode=’tag’, tagValue=’Fraser syndrome’]