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Duodenal atresia is the congenital absence or complete closure of a portion of the lumen of the duodenum.
Approximately 20-40% of all infants with duodenal atresia have Down syndrome.[citation needed]. Approximately 8% all infants with Down syndrome have duodenal atresia.[1]
It is also associated with polyhydramnios, which is increased amniotic fluid in the uterus.[1]
The diagnosis of duodenal atresia is usually confirmed by radiography. An X-ray of the abdomen shows two large air filled spaces, the so-called “double bubble” sign.[2] [3] The air is trapped in the stomach and duodenum. Since the closure of the duodenum is complete in duodenal atresia, no air is seen distal to the duodenum.
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